Our 6- and 8-year-olds loved these cartoons, and it was a kick for me to see episodes I hadn't seen since childhood. However, please be aware that in addition to the smoking mentioned in the main review, the complete collection on DVD contains episodes that deal comically and blatantly with alcoholism and drunkeness. Went over my kids' heads at the time, but I was waiting for some awkward questions.
My 4yr old absolutely loves Pink Panther and finds him hysterical. Granted, yes, it does have pipe and cigarette smoking, but you'll find those in real life. Also, having an exploding cigar is a bit of a deterrent from smoking.
If you're sensitive to guns, I think there's some guns in there but if you're a responsible parent watching this with your kids, you can explain everything in there.