Love this game! The audio from the show and the cutaway gags to actual Family Guy cutaway gags make it extremely enjoyable. (I also must say CSM made an excellent review of the content in the game, which is more than I can usually say.)
LANGUAGE: "B-tch", "Holy cr-p", "D-mmit", "What the H-ll?" etc., plus two censored expletives after you beat the last level (Brian yells, "Yeah! In your f-cking face, f-ck wad!" from the Family Guy episode "Petarded", but the subtitle just says, "In your face!", and the f-words are bleeped out, just like on TV.)
SEX: Quagmire mentions how one of Stewie's toys won't fit up his an-s, and there's some other sexual humor in the game, plus actual clips from the show which MIGHT be raunchy (I haven't unlocked them all yet; the ones I saw weren't TOO bad from what I remember, but expect anything you would expect from the show.)
The other categories were already reviewed quite nicely above. Again, it's a really enjoyable game, especially if you enjoy the TV show.