For a Disney Channel show, GLC is a great sitcom for all ages to enjoy - yes, even ADULTS. It's not annoying like the rest of the DC shows, which is awesome.
GLC basically summarizes: the Duncan family, parents Bob and Amy and their four children (later five) named P.J., Teddy, Gabe, Charlie, and eventually Toby, who manages to survive through their crazy but enjoyable and laughable life.
Each and every character is realistic and relatable and well-written.
Bob is an exterminator, a lovable goofball, is overweight (and constantly made fun of for his weight especially by Gabe), loves junk food, and slightly lazy but works hard to support his family.
Amy is, IMO, the most hilarious character on GLC. She's also the craziest. She's very proud and happy being a mother of a large family (and seems to want more kids). Though, she can be a bit self-centered, which is played in a humorous way. She often likes to tell stories about her college years, embarrasses her kids (especially Teddy) and even her husband, and loves being in the spotlight (maybe a bit too much). She does genuinely care about her kids and husband, however. She's always there to give out advice (not always the best advice, though) and comfort them.
P.J. is the oldest child but the most irresponsible and "dumbest". He seems to lack common sense, is very childish, but also very lovable and sweet and concerned about others. He's a "musician" (a very bad one at that, though it's supposed to be for laughs) and totally girl-crazy. He is very talented in one area: cooking. In fact, later, he decides to become a cook.
Teddy is the oldest daughter who comes across as mature and responsible for her age (of course, she does mess up sometimes), funny and charming, popular at school, smart, and a great sister, especially to Charlie (in fact, she makes video diaries for her!). She's mostly a "goody-goody", though she does lies and rebels in order to get her way. She always learns a lesson from her parents, though. She is very much like her mother, always loving attention, though not as crazy. She takes an interest in acting, singing, and journalism. She is also boy-crazy. She gets into quite a few relationships with boys, but she has one serious and off-and-on relationship with Spencer Walsh.
Gabe is the middle child and goes through an awkward preteen and teen phase. He's very clever, witty, and mischievous. He's known as a troublemaker and is proud of it (however, his mischief always fails at the end, and somebody - usually Amy or Bob - teaches him a lesson). He is not fond of Charlie, for he was the youngest for ten years of his life and she was an unexpected surprise. Though, he does sometime share genuine love and care to her. I feel, though, that by the third and fourth season, he became boring and flat and meaningless. For the first two seasons, though, he was fabulous.
Charlie was originally an adorable and sweet but sometimes mischievous in her own way baby and toddler. She eventually becomes a preschooler, but remains a cutie pie. :) When Toby (the 5th child) was born, she didn't become fond of him at ALL. (Fun fact: she and Toby shares the same birthday!)
Toby is the youngest and last child of the Duncan family. I don't really like him, though. He wasn't cute and funny and sweet as Charlie. To me, he was more of a "prop" if you know what I mean.
So, GLC was amazing. Well, for the first 2 seasons. The last 2 went downhill. Yeah, it was sad that GLC had to end, but it's probably best for them to end anyway, for it wasn't a very good show by then.