Blind since childhood, concert violinist Sydney (
Jessica Alba) gets a cornea transplant and promptly begins seeing the same fearsome visions (warnings of deaths, visits from ghosts, etc.) that troubled the donor. Feeling abandoned by her loving but rarely available sister (
Parker Posey) and increasingly unable to differentiate between her nightmarish visions and new glimpses of a daunting material world, Sydney seeks help from her therapist, Paul (
Alessandro Nivola), and her conductor/mentor, Simon (Rade Serbedzija). Neither man is helpful, so Sydney sets off on her own, researching possible causes and then seeking the donor, who turns out to be a young Mexican woman named Ana (Fernanda Romero). Eventually, Sydney heads to Mexico with Paul; their efforts lead to a resolution, but not without costs.