An unstoppable, lethal plague virus -- unexplained but hinted at originating in Asia -- transmitted by touch and by breath from person to person, has devastated humankind worldwide. By the time this movie opens, most people are dead, no organized society remains, and it's every man for himself. College-age brothers Brian (
Chris Pine) and his younger, brainy sibling Daniel (
Lou Taylor Pucci), and their girlfriends drive a stolen car to a well-remembered childhood beach-resort, evidently in the Gulf of Mexico, where Brian and Daniel plan to wait out the plague with their surfboards. But, as they encounter other scattered, sometimes dangerous survivors, infection, deceit, and desperation tear the foursome apart.