This show is mostly just for laughs and it accomplishes that pretty well. L.O.S.E outshines many of those other dumb shows out there (e.g. new episodes of SpongeBob and Fairly odd parents, life with boys, big time rush, and many others).
The animation has its unique style, the plots are ridiculous but funny, and the characters have their own personalities.
I'm really disappointed that they have ended the series. The final episode was a remarkable ending but the series is over. Go watch this show!