Osmosis Jones Movie Poster Image

Osmosis Jones



Mostly animated PG film has gross-out humor, violence.
Popular with kids
  • Review Date: June 17, 2003
  • Rated: PG
  • Genre: Comedy
  • Release Year: 2001
  • Running Time: 95 minutes

What parents need to know

Positive messages

In its own strange way, the film promotes healthy eating and living.

Positive role models

In the live-action sequences, Shane loves her Dad very much, in spite of all the mistakes he makes, and wants him to be healthy.


Cartoonish violence. During the animated sequences, characters get into fistfights, car chases, and gun battles between white blood cell police officers and green viruses dressed like criminals. During the life-action sequences, a character vomits on another character. A character fights a monkey for a hard-boiled egg after the monkey takes the egg out of his hand. Characters are killed and there is one apparent death.


During the animated sequences, personified male and female white blood cells passionately kiss, A personified male white blood cell talks to a personified female white blood cell about "hooking up," and the female white blood cell rejects him by making a masturbation reference.


Not really an issue, but characters say the word "spit" as an obvious substitution for "s--t."

Not applicable
Drinking, drugs, & smoking

During the live-action sequences a character is always shown smoking a cigar. This same character encourages a character who seems to be coming down with a cold to drink a beer as quickly as possible, which this character does. During the animation sequences, characters go into a bar that is inside of a pimple, where they drink drinks made to look like alcoholic beverages.

Parents Need to Know

Parents need to know that Osmosis Jones is a mix of live-action and animation, and is also a mix of puerile humor and cartoonish violence. While the animated sequences are imaginative, and Bill Murray is always entertaining, there is vomiting, pimple popping, snot, and flatulence. One of the main characters in the live-action sequences is always shown smoking a cigar, and in the animated sequences, a male white blood cell talks to a female white blood cell about "hooking up," and the female white blood cell makes a reference to masturbation. Parents should also know that the movie features a child whose mother has died and who is terribly worried about losing her father, who seems bent on suicide by junk food. Some kids will be upset by the way that the child has to assume the role of parent.

What's the story?

OSMOSIS JONES is a PG-rated, mostly animated movie about a very hip white blood cell (Chris Rock) and a cold capsule (David Hyde Pierce) who fight a nasty virus (Laurence Fishburne) to save the scrofulous body of zoo attendant Frank (Bill Murray). The live-action story, starring Murray with Elena Franklin as his daughter, Chris Elliott as his friend, and a brief, effervescent appearance by Molly Shannon as Shane's teacher, takes up about a quarter of movie. The rest takes place inside Frank's body, a swarming metropolis with white cell cops fighting off everything from gingivitis to intestinal unpleasantness.

Is it any good?


The Farrelly brothers and their crude humor have plumbed new depths of internal plumbing in Osmosis Jones. It seems an appropriate follow-up to the brothers' There's Something About Mary, which plumbed new depths of bodily function humor (and ended up on the American Film Institute's list of the 100 funniest movies).

The details -- and many of the jokes -- may be a little hard to follow for anyone who does not have a working knowledge of anatomy. But the basic story line of a cop who likes to do things his way paired up with a straight-arrow, by-the-books partner joining forces against a lethal bad guy is standard movie stuff, and, as usual, it works pretty well.

Families can talk about...

  • Families can talk about how we keep our bodies strong enough to fight off infection and viruses, and the challenge of deciding between things that feel good now and those that feel good later. How does that relate to the choice between the two candidates for mayor?

  • Talk about the news broadcasts that the characters inside of Frank watch. If there was one going on inside you, what would it say?

  • How well does your family take care of itself? What can you do to be healthier?

Movie details

Theatrical release date:August 10, 2001
DVD release date:November 13, 2001
Cast:Brandy Norwood, Chris Rock, David Hyde Pierce
Directors:Bobby Farrelly, Peter Farrelly
Studio:Warner Bros.
Topics:Adventures, Science and nature
Run time:95 minutes
MPAA rating:PG
MPAA explanation:bodily humor

This review of Osmosis Jones was written by

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Learning ratings

  • Best: Really engaging; great learning approach.
  • Very Good: Engaging; good learning approach.
  • Good: Pretty engaging; good learning approach.
  • Fair: Somewhat engaging; OK learning approach.
  • Not for Learning: Not recommended for learning.
  • Not for Kids: Not age-appropriate for kids; not recommended for learning.

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Kid, 11 years old December 27, 2012

A Grossed Out Film

Well, let me tell the story how I first saw this film. I saw it in science class and I had to answer these questions. This made me laugh and grossed out. It's a funny film,but messed up. You see, this movie was supposed to be rated PG-13 then they switched to PG (you know, to be family-friendly) Scenes like adult like. One deleted scene was where the two characters visit sperm cells in Frank's body. One scene in the film where cells were making out. One was when Frank's pal gives him beer to drink. When the male cell tells a female cell about hooking-up and the female taking a joke about masturbating .Another scene is where in the mayor's office, there's a statue of a sperm cell. Another is when the Frank pukes all over his daughter's teacher and they show it in the movie! That will make your kids wanting to puke.One specially gross scene where the two heroes try to find the bad guy and his crew. They go to a club and then there was this rapper called "Kidney Rock" (just like you guessed it, "Kid Rock") and while all this happens, they show cells strip-dancing!!! And there's another scene where a character drinks a beverage that looks like beer. Lastly, when the characters mentions the uvvala and the character thinks its in his boxer shorts when it's his throat. This movie's so down in the dumps. It shows great scientific facts to learn but, it's gross in a way to it. I just can't stand that film. For me, I would recommend something better to watch.
What other families should know
Great role models
Too much violence
Too much sex
Too much swearing
Too much consumerism
Too much drinking/drugs/smoking
Adult Written bycrap April 9, 2008

I do not agree

For any parents checking this movie is not as aprprote as you think there are very sad scenes at the end there is a big fight. Words such as hell are used. And a slopp is killed in a very sad way. [Don't worry after you cry he comes back to life.] This should have a PG-13 rating.
Teen, 13 years old Written bysupersonic7896 March 29, 2012

kids of plymouth watch

before the true rateing i must say i am from plymouth. if anyone who goes to nmes will look at the school in movie and hospital scean it might look firmiliar. i saw when i was younger and liked it watched its show. grossness bothers you when older rather than younger cause when your younger you dont know its gross.
What other families should know
Too much violence


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