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Osmosis Jones

Movie review by
Nell Minow, Common Sense Media
Osmosis Jones Movie Poster Image
Mostly animated PG film has gross-out humor, violence.
  • PG
  • 2001
  • 95 minutes
Popular with kids

Parents say

age 8+
Based on 9 reviews

Kids say

age 9+
Based on 23 reviews

A lot or a little?

The parents' guide to what's in this movie.

Positive Messages

In its own strange way, the film promotes healthy eating and living.

Positive Role Models & Representations

In the live-action sequences, Shane loves her Dad very much, in spite of all the mistakes he makes, and wants him to be healthy.


Cartoonish violence. During the animated sequences, characters get into fistfights, car chases, and gun battles between white blood cell police officers and green viruses dressed like criminals. During the life-action sequences, a character vomits on another character. A character fights a monkey for a hard-boiled egg after the monkey takes the egg out of his hand. Characters are killed and there is one apparent death.


During the animated sequences, personified male and female white blood cells passionately kiss, A personified male white blood cell talks to a personified female white blood cell about "hooking up," and the female white blood cell rejects him by making a masturbation reference.


Not really an issue, but characters say the word "spit" as an obvious substitution for "s--t."

Drinking, Drugs & Smoking

During the live-action sequences a character is always shown smoking a cigar. This same character encourages a character who seems to be coming down with a cold to drink a beer as quickly as possible, which this character does. During the animation sequences, characters go into a bar that is inside of a pimple, where they drink drinks made to look like alcoholic beverages.

What parents need to know

Parents need to know that Osmosis Jones is a mix of live-action and animation, and is also a mix of puerile humor and cartoonish violence. While the animated sequences are imaginative, and Bill Murray is always entertaining, there is vomiting, pimple popping, snot, and flatulence. One of the main characters in the live-action sequences is always shown smoking a cigar, and in the animated sequences, a male white blood cell talks to a female white blood cell about "hooking up," and the female white blood cell makes a reference to masturbation. Parents should also know that the movie features a child whose mother has died and who is terribly worried about losing her father, who seems bent on suicide by junk food. Some kids will be upset by the way that the child has to assume the role of parent.

User Reviews

  • Parents say
  • Kids say
Adult Written bySuper_JRM May 18, 2018

An amazing film

It was ok. A great movie that will capture the hearts of many. It has action, suspense, and great morals. It is a great film that anyone will enjoy!
Adult Written byEZL1414 November 11, 2014

Not very accurate, Some innuendos are made

Except for the part about cold medicine only relieving your systems instead of curing the disease, I would like to say that this movie is scientifically inaccur... Continue reading
Kid, 9 years old June 17, 2011


Very very gross! I couldn't eat very well after I saw the movie. This is NOT appropriate for kids! I saw it at school and the other kids in my class lik... Continue reading
Teen, 14 years old Written bysisterwhocares December 9, 2011

Not bad, rather educational. A bit corny, but good for 5th/6th graders.

I actually watched this movie in my health class, and it is rather educational. Most of the inappropriate stuff is just potty humor. It does give some good fact... Continue reading

What's the story?

OSMOSIS JONES is a PG-rated, mostly animated movie about a very hip white blood cell (Chris Rock) and a cold capsule (David Hyde Pierce) who fight a nasty virus (Laurence Fishburne) to save the scrofulous body of zoo attendant Frank (Bill Murray). The live-action story, starring Murray with Elena Franklin as his daughter, Chris Elliott as his friend, and a brief, effervescent appearance by Molly Shannon as Shane's teacher, takes up about a quarter of movie. The rest takes place inside Frank's body, a swarming metropolis with white cell cops fighting off everything from gingivitis to intestinal unpleasantness.

Is it any good?

The Farrelly brothers and their crude humor have plumbed new depths of internal plumbing in Osmosis Jones. It seems an appropriate follow-up to the brothers' There's Something About Mary, which plumbed new depths of bodily function humor (and ended up on the American Film Institute's list of the 100 funniest movies).

The details -- and many of the jokes -- may be a little hard to follow for anyone who does not have a working knowledge of anatomy. But the basic story line of a cop who likes to do things his way paired up with a straight-arrow, by-the-books partner joining forces against a lethal bad guy is standard movie stuff, and, as usual, it works pretty well.

Talk to your kids about ...

  • Families can talk about how we keep our bodies strong enough to fight off infection and viruses, and the challenge of deciding between things that feel good now and those that feel good later. How does that relate to the choice between the two candidates for mayor?

  • Talk about the news broadcasts that the characters inside of Frank watch. If there was one going on inside you, what would it say?

  • How well does your family take care of itself? What can you do to be healthier?

Movie details

Themes & Topics

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For kids who love animation and humor

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